Ontology highlight
ABSTRACT:
SUBMITTER: Fischer WB
PROVIDER: S-EPMC7094687 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Biochimica et biophysica acta 20160122 7 Pt B
Viral channel forming proteins (VCPs) have been discovered in the late 70s and are found in many viruses to date. Usually they are small and have to assemble to form channels which depolarize the lipid membrane of the host cells. Structural information is just about to emerge for just some of them. Thus, computational methods play a pivotal role in generating plausible structures which can be used in the drug development process. In this review the accumulation of structural data is introduced f ...[more]