Deceased Brain Dead Donor Liver Transplantation and Utilization in the United States: Nighttime and Weekend Effects.

ABSTRACT:

Background

Understanding factors that contribute to liver discards and nonusage is urgently needed to improve organ utilization.

Methods

Using Scientific Registry of Transplant Recipient data, we studied a national cohort of all US adult, deceased brain dead donor, isolated livers available for transplantation from 2003 to 2016, including organ-specific and system-wide factors that may affect organ procurement and discard rates.

Results

Of 73 686 available livers, 65 316 (88.64%) were recovered for transplant, of which 6454 (9.88%) were ultimately discarded. Livers that were not procured or, on recovery, discarded were more frequently from older, heavier, hepatitis B virus (HCV)+, and more comorbid donors (P < 0.001). However, even after adjustment for organ quality,

SUBMITTER: Carpenter DJ 

PROVIDER: S-EPMC7096151 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature