Ontology highlight
ABSTRACT:
SUBMITTER: Rivera C
PROVIDER: S-EPMC7096434 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Rivera César C Crisóstomo Mariangela Fernanda MF Peña Carolina C González-Díaz Paulina P González-Arriagada Wilfredo Alejandro WA
Scientific reports 20200325 1
Today, we face difficulty in generating new hypotheses and understanding oral lichen planus due to the large amount of biomedical information available. In this research, we have used an integrated bioinformatics approach assimilating information from data mining, gene ontologies, protein-protein interaction and network analysis to predict candidate genes related to oral lichen planus. A detailed pathway analysis led us to propose two promising therapeutic targets: the stromal cell derived facto ...[more]