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Infant behavioral reactivity predicts change in amygdala volume 12 years later.

ABSTRACT: The current study examined the link between temperamental reactivity in infancy and amygdala development in middle childhood. A sample (n = 291) of four-month-old infants was assessed for infant temperament, and two groups were identified: those exhibiting negative reactivity (n = 116) and those exhibiting positive reactivity (n = 106). At 10 and 12 years of age structural imaging was completed on a subset of these participants (n = 75). Results indicate that, between 10 and 12 years of age, left amygdala volume increased more slowly in those with negative compared to positive reactive temperament. These results provide novel evidence linking early temperament to distinct patterns of brain development over middle childhood.

SUBMITTER: Filippi CA

PROVIDER: S-EPMC7096757 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Infant behavioral reactivity predicts change in amygdala volume 12 years later.

Filippi Courtney A CA Sachs Jessica F JF Phillips Dominique D Winkler Anderson A Gold Andrea L AL Leibenluft Ellen E Pine Daniel S DS Fox Nathan A NA

Developmental cognitive neuroscience 20200321

The current study examined the link between temperamental reactivity in infancy and amygdala development in middle childhood. A sample (n = 291) of four-month-old infants was assessed for infant temperament, and two groups were identified: those exhibiting negative reactivity (n = 116) and those exhibiting positive reactivity (n = 106). At 10 and 12 years of age structural imaging was completed on a subset of these participants (n = 75). Results indicate that, between 10 and 12 years of age, lef ...[more]

PMID: 32452462

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