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Ibis T5000: a universal biosensor approach for microbiology.


ABSTRACT: We describe a new technology, the Ibis T5000, for the identification of pathogens in clinical and environmental samples. The Ibis T5000 couples nucleic acid amplification to high-performance electrospray ionization mass spectrometry and base-composition analysis. The system enables the identification and quantification of a broad set of pathogens, including all known bacteria, all major groups of pathogenic fungi and the major families of viruses that cause disease in humans and animals, along with the detection of virulence factors and antibiotic resistance markers.

SUBMITTER: Ecker DJ 

PROVIDER: S-EPMC7097577 | biostudies-literature | 2008 Jul

REPOSITORIES: biostudies-literature

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Ibis T5000: a universal biosensor approach for microbiology.

Ecker David J DJ   Sampath Rangarajan R   Massire Christian C   Blyn Lawrence B LB   Hall Thomas A TA   Eshoo Mark W MW   Hofstadler Steven A SA  

Nature reviews. Microbiology 20080603 7


We describe a new technology, the Ibis T5000, for the identification of pathogens in clinical and environmental samples. The Ibis T5000 couples nucleic acid amplification to high-performance electrospray ionization mass spectrometry and base-composition analysis. The system enables the identification and quantification of a broad set of pathogens, including all known bacteria, all major groups of pathogenic fungi and the major families of viruses that cause disease in humans and animals, along w  ...[more]

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