Ontology highlight
ABSTRACT:
SUBMITTER: Yu B
PROVIDER: S-EPMC7098381 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Nanomedicine : nanotechnology, biology, and medicine 20200123
Iron oxide nanoparticles (IONPs) have been increasingly used in various biomedical applications in preclinical and clinical settings. Although the interactions of IONPs with macrophages have been well-reported in the context of nanoparticle toxicity, harnessing the capacity of IONPs in reprograming macrophages towards bactericidal activity has not been explored. Here, using an in vitro culture model of macrophages and an in vivo mouse model of skin wound infection by Staphylococcus aureus (S. au ...[more]