Geranylated Coumarins From Thai Medicinal Plant Mammea siamensis With Testosterone 5?-Reductase Inhibitory Activity.
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ABSTRACT:
SUBMITTER: Morikawa T
PROVIDER: S-EPMC7099204 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
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Geranylated Coumarins From Thai Medicinal Plant <i>Mammea siamensis</i> With Testosterone 5α-Reductase Inhibitory Activity.
Morikawa Toshio T Luo Fenglin F Manse Yoshiaki Y Sugita Hidemi H Saeki Shunsuke S Chaipech Saowanee S Pongpiriyadacha Yutana Y Muraoka Osamu O Ninomiya Kiyofumi K
Frontiers in chemistry 20200320
Geranylated coumarin constituents, kayeassamin I (<b>1</b>) and mammeasins E (<b>2</b>) and F (<b>3</b>) were newly isolated from the methanol extract of the flowers of <i>Mammea siamensis</i> (Calophyllaceae) originating in Thailand, along with five known isolates, such as mammea E/BC (<b>23</b>), deacetylmammea E/AA cyclo D (<b>31</b>), deacetylmammea E/BB cyclo D (<b>32</b>), mammea A/AA cyclo F (<b>34</b>), and mammea A/AC cyclo F (<b>35</b>). These compounds (<b>1</b>-<b>3</b>) were obtaine ...[more]
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