Ontology highlight
ABSTRACT:
SUBMITTER: Francipane MG
PROVIDER: S-EPMC7099580 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Francipane Maria Giovanna MG Han Bing B Oxburgh Leif L Sims-Lucas Sunder S Li Zhongwei Z Lagasse Eric E
Journal of tissue engineering and regenerative medicine 20190730 9
Stem cell-derived organoids are emerging as sophisticated models for studying development and disease and as potential sources for developing organ substitutes. Unfortunately, although organoids containing renal structures have been generated from mouse and human pluripotent stem cells, there are still critical unanswered questions that are difficult to attain via in vitro systems, including whether these nonvascularized organoids have a stable and physiologically relevant phenotype or whether a ...[more]