Ontology highlight
ABSTRACT:
SUBMITTER: Chiesa G
PROVIDER: S-EPMC7099826 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Chiesa Giulio G Kiriakov Szilvia S Khalil Ahmad S AS
BMC biology 20200326 1
The traditional view of protein aggregation as being strictly disease-related has been challenged by many examples of cellular aggregates that regulate beneficial biological functions. When coupled with the emerging view that many regulatory proteins undergo phase separation to form dynamic cellular compartments, it has become clear that supramolecular assembly plays wide-ranging and critical roles in cellular regulation. This presents opportunities to develop new tools to probe and illuminate t ...[more]