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Global stability analysis for a generalized delayed SIR model with vaccination and treatment.

ABSTRACT: In this work, we investigate the stability of an SIR epidemic model with a generalized nonlinear incidence rate and distributed delay. The model also includes vaccination term and general treatment function, which are the two principal control measurements to reduce the disease burden. Using the Lyapunov functions, we show that the disease-free equilibrium state is globally asymptotically stable if R0?1 , where R0 is the basic reproduction number. On the other hand, the disease-endemic equilibrium is globally asymptotically stable when R0>1 . For a specific type of treatment and incidence functions, our analysis shows the success of the vaccination strategy, as well as the treatment depends on the initial size of the susceptible population. Moreover, we discuss, numerically, the behavior of the basic reproduction number with respect to vaccination and treatment parameters.

SUBMITTER: Elazzouzi A

PROVIDER: S-EPMC7100696 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Global stability analysis for a generalized delayed SIR model with vaccination and treatment.

Elazzouzi A A Lamrani Alaoui A A Tilioua M M Tridane A A

Advances in difference equations 20191221 1

In this work, we investigate the stability of an SIR epidemic model with a generalized nonlinear incidence rate and distributed delay. The model also includes vaccination term and general treatment function, which are the two principal control measurements to reduce the disease burden. Using the Lyapunov functions, we show that the disease-free equilibrium state is globally asymptotically stable if R 0 ≤ 1 , where R 0 is the basic reproduction number. On the other hand, the disease-endemic equi ...[more]

PMID: 32226453

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Dataset Information

Global stability analysis for a generalized delayed SIR model with vaccination and treatment.

Publications

Global stability analysis for a generalized delayed SIR model with vaccination and treatment.

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