Multiplex real-time PCR for prompt diagnosis of an outbreak of human parainfluenza 3 virus in children with acute leukemia.
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ABSTRACT:
SUBMITTER: Berrueco R
PROVIDER: S-EPMC7100800 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Publications
Multiplex real-time PCR for prompt diagnosis of an outbreak of human parainfluenza 3 virus in children with acute leukemia.
Berrueco R R Antón A A Rives S S Català A A Toll T T Ruiz A A Camós M M Torrebadell M M Estella J J Muñoz-Almagro C C
Infection 20130703 6
<h4>Introduction</h4>Human parainfluenza virus type 3 (HPIV-3) causes significant morbimortality in immunocompromised patients. Outbreaks of severe pneumonitis have been previously described in this setting.<h4>Materials and methods</h4>Retrospective observational study in children diagnosed with acute leukemia and a documented HPIV-3 infection in the context of a nosocomial outbreak occurred in a single center.<h4>Result</h4>During summer 2012, an HPIV-3 infection was detected in six hospitaliz ...[more]
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