Dataset Information

Controlling infectious disease outbreaks in low-income and middle-income countries.

ABSTRACT: When an infectious disease outbreak is detected or suspected, a healthcare facility's infection control personnel should be notified and an outbreak control team formed that is pertinent to the size and severity of the outbreak and healthcare facility. Management of an infectious disease outbreak in a middle- or low-income country is challenging. Cost-effective recommendations that are easy to carry out and that have been stratified according to the type of infection and prevention and control intervention used are provided in this paper and constitute basic practices.

SUBMITTER: Caeiro JP

PROVIDER: S-EPMC7100832 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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Controlling infectious disease outbreaks in low-income and middle-income countries.

Caeiro Juan Pablo JP Garzón María I MI

Current treatment options in infectious diseases 20180215 1

When an infectious disease outbreak is detected or suspected, a healthcare facility's infection control personnel should be notified and an outbreak control team formed that is pertinent to the size and severity of the outbreak and healthcare facility. Management of an infectious disease outbreak in a middle- or low-income country is challenging. Cost-effective recommendations that are easy to carry out and that have been stratified according to the type of infection and prevention and control i ...[more]

PMID: 32226321

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Project description:BACKGROUND: Infectious disease outbreaks in communities can be controlled by early detection and effective prevention measures. Assessing the relative importance of each individual community member with respect to these two processes requires detailed knowledge about the underlying social contact network on which the disease can spread. However, mapping social contact networks is typically too resource-intensive to be a practical possibility for most communities and institutions. METHODS: Here, we describe a simple, low-cost method - called collocation ranking - to assess individual importance for early detection and targeted intervention strategies that are easily implementable in practice. The method is based on knowledge about individual collocation which is readily available in many community settings such as schools, offices, hospitals, and so on. We computationally validate our method in a school setting by comparing the outcome of the method against computational predictions based on outbreak simulations on an empirical high-resolution contact network. We compare collocation ranking to other methods for assessing the epidemiological importance of the members of a population. To this end, we select subpopulations of the school population by applying these assessment methods to the population and adding individuals to the subpopulation according to their individual rank. Then, we assess how suited these subpopulations are for early detection and targeted intervention strategies. RESULTS: Likelihood and timing of infection during an outbreak are important features for early detection and targeted intervention strategies. Subpopulations selected by the collocation ranking method show a substantially higher average infection probability and an earlier onset of symptoms than randomly selected subpopulations. Furthermore, these subpopulations selected by the collocation ranking method were close to the optimum. CONCLUSIONS: Our results indicate that collocation ranking is a highly effective method to assess individual importance, providing critical low-cost information for the development of sentinel surveillance systems and prevention strategies.

Dataset Information

Controlling infectious disease outbreaks in low-income and middle-income countries.

Publications

Controlling infectious disease outbreaks in low-income and middle-income countries.

Similar Datasets

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