Ontology highlight
ABSTRACT:
SUBMITTER: Fisher AL
PROVIDER: S-EPMC7101151 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Fisher Allison L AL Sangkhae Veena V Presicce Pietro P Chougnet Claire A CA Jobe Alan H AH Kallapur Suhas G SG Tabbah Sammy S Buhimschi Catalin S CS Buhimschi Irina A IA Ganz Tomas T Nemeth Elizabeta E
JCI insight 20200227 4
Adequate iron supply during pregnancy is essential for fetal development. However, how fetal or amniotic fluid iron levels are regulated during healthy pregnancy, or pregnancies complicated by intraamniotic infection or inflammation (IAI), is unknown. We evaluated amniotic fluid and fetal iron homeostasis in normal and complicated murine, macaque, and human pregnancy. In mice, fetal iron endowment was affected by maternal iron status, but amniotic fluid iron concentrations changed little during ...[more]