Ontology highlight
ABSTRACT:
SUBMITTER: Costa J
PROVIDER: S-EPMC7101329 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Costa Júlia J Pronto-Laborinho Ana A Pinto Susana S Gromicho Marta M Bonucci Sara S Tranfield Erin E Correia Catarina C Alexandre Bruno M BM de Carvalho Mamede M
Scientific reports 20200327 1
Galectin-3 binding protein (LGALS3BP or 90 K) is a secreted glycoprotein found in human body fluids. Deregulated levels were observed in cancer and infection and its study in neurological diseases is more recent. Here, we have investigated 90 K from human cerebrospinal fluid (CSF) of patients with amyotrophic lateral sclerosis (ALS, n = 35) and other neurological diseases (n = 23). CSF was fractionated by ultrafiltration/size-exclusion chromatography (SEC) and eluted fractions were analysed by c ...[more]