Ontology highlight
ABSTRACT:
SUBMITTER: Shimada YJ
PROVIDER: S-EPMC7102897 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Shimada Yuichi J YJ Hasegawa Kohei K Kochav Stephanie M SM Mohajer Pouya P Jung Jeeyoun J Maurer Mathew S MS Reilly Muredach P MP Fifer Michael A MA
Journal of cardiovascular translational research 20190705 6
High-throughput proteomics profiling has never been applied to discover biomarkers in patients with hypertrophic cardiomyopathy (HCM). The objective was to identify plasma protein biomarkers that can distinguish HCM from controls. We performed a case-control study of patients with HCM (n = 15) and controls (n = 22). We carried out plasma proteomics profiling of 1129 proteins using the SOMAscan assay. We used the sparse partial least squares discriminant analysis to identify 50 most discriminant ...[more]