Ontology highlight
ABSTRACT:
SUBMITTER: Camorani S
PROVIDER: S-EPMC7103779 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Camorani Simona S Granata Ilaria I Collina Francesca F Leonetti Francesco F Cantile Monica M Botti Gerardo G Fedele Monica M Guarracino Mario Rosario MR Cerchia Laura L
iScience 20200312 4
Triple-negative breast cancer (TNBC) is a high heterogeneous group of tumors with a distinctly aggressive nature and high rates of relapse. So far, the lack of any known targetable proteins has not allowed a specific anti-tumor treatment. Therefore, the identification of novel agents for specific TNBC targeting and treatment is desperately needed. Here, by integrating cell-SELEX (Systematic Evolution of Ligands by EXponential enrichment) for the specific recognition of TNBC cells with high-throu ...[more]