Ontology highlight
ABSTRACT:
SUBMITTER: Jan M
PROVIDER: S-EPMC7104869 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Jan Maxime M O'Hara Bruce F BF Franken Paul P
F1000Research 20200327
Sleep is a ubiquitous and complex behavior in both its manifestation and regulation. Despite its essential role in maintaining optimal performance, health, and well-being, the genetic mechanisms underlying sleep remain poorly understood. Here, we review the forward genetic approaches undertaken in the last four years to elucidate the genes and gene pathways affecting sleep and its regulation. Despite an increasing number of studies and mining large databases, a coherent picture on "sleep" genes ...[more]