Ontology highlight
ABSTRACT:
SUBMITTER: Weng J
PROVIDER: S-EPMC7105466 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Weng Junyong J Li Shanbao S Lin Hao H Mei Haitao H Liu Yang Y Xiao Chao C Zhu Zhonglin Z Cai Weiwei W Ding Xusheng X Mi Yushuai Y Wen Yugang Y
Cell death & disease 20200330 3
Gastric cancer (GC) has a high mortality rate, and metastasis is the main reason for treatment failure. It is important to study the mechanism of tumour invasion and metastasis based on the regulation of key genes. In a previous study comparing the expression differences between GES-1 and SGC-7901 cells, PCDHGA9 was selected for further research. In vitro and in vivo experiments showed that PCDHGA9 inhibited invasion and metastasis. A cluster analysis suggested that PCDHGA9 inhibited epithelial- ...[more]