Ontology highlight
ABSTRACT:
SUBMITTER: Kim CY
PROVIDER: S-EPMC7105546 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Kim Chae Young CY Kang Bobin B Hong Jungil J Choi Hyeon-Son HS
Food science and biotechnology 20190826 3
The effects of parthenolide (PL), a sesquiterpene lactone obtained from feverfew plant, on lipid accumulation and signaling pathway in adipocytes were investigated. PL significantly inhibited lipid accumulation and adipogenic factors during adipogenesis. In particular, PL exerted its inhibitory effects in early adipogenic stage by regulating the early adipogenic factors. In addition, PL regulated the expression of adipokines; leptin, retinol binding protein, and resistin mRNAs were downregulated ...[more]