Nuclear Factor ?B (NF-?B)-Mediated Inflammation in Multiple Sclerosis.
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ABSTRACT:
SUBMITTER: Zhou Y
PROVIDER: S-EPMC7105607 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Nuclear Factor κB (NF-κB)-Mediated Inflammation in Multiple Sclerosis.
Zhou Yifan Y Cui Chunping C Ma Xiaoyu X Luo Wenjing W Zheng Song Guo SG Qiu Wei W
Frontiers in immunology 20200324
The nuclear factor κB (NF-κB) signaling cascade has been implicating in a broad range of biological processes, including inflammation, cell proliferation, differentiation, and apoptosis. The past three decades have witnessed a great progress in understanding the impact of aberrant NF-κB regulation on human autoimmune and inflammatory disorders. In this review, we discuss how aberrant NF-κB activation contributes to multiple sclerosis, a typical inflammatory demyelinating disease of the central n ...[more]
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