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Time scale evolution of avipoxviruses.

ABSTRACT: Avipoxviruses are divided into three clades: canarypox-like viruses, fowlpox-like viruses, and psittacinepox-like viruses. Several molecular clock and demographic models available in the BEAST package were compared on three avipoxvirus genes (P4b, cnpv186 and DNA polymerase genes), which enabled to determine that avipoxviruses evolved at a rate of 2-8×10(-5)substitution/site/year, in the range of poxviruses previously reported evolution rates. In addition, the date of mean time of divergence of avipoxviruses from a common ancestor was extrapolated to be about 10,000-30,000years ago, at the same period as modern poxvirus species. Our findings will facilitate epidemiological investigations on avipoxviruses' spread, origin and circulation.

SUBMITTER: Le Loc'h G

PROVIDER: S-EPMC7106339 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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Time scale evolution of avipoxviruses.

Le Loc'h Guillaume G Bertagnoli Stéphane S Ducatez Mariette F MF

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20150729

Avipoxviruses are divided into three clades: canarypox-like viruses, fowlpox-like viruses, and psittacinepox-like viruses. Several molecular clock and demographic models available in the BEAST package were compared on three avipoxvirus genes (P4b, cnpv186 and DNA polymerase genes), which enabled to determine that avipoxviruses evolved at a rate of 2-8×10(-5)substitution/site/year, in the range of poxviruses previously reported evolution rates. In addition, the date of mean time of divergence of ...[more]

PMID: 26231721

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