Dataset Information

Effects of Interim Buprenorphine Treatment for opioid use disorder among emerging adults.

ABSTRACT:

Objective

Although opioid maintenance is a first-line approach for treating opioid use disorder (OUD), suboptimal treatment outcomes have been reported among emerging adults (EAs; 18-25 years of age). In this secondary analysis, we compared treatment outcomes between EAs and older adults (OAs; ? 26 years of age) receiving low-barrier, technology-assisted Interim Buprenorphine Treatment (IBT) during waitlist delays to comprehensive opioid maintenance treatment.

Method

Participants were 35 individuals with OUD who received IBT consisting of 12-weeks of buprenorphine maintenance with bi-monthly clinic visits and technology-assisted monitoring. At monthly follow-up assessments, participants completed staff-observed urinalysis, the Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI-II), and Addiction Severity Index (ASI).

Results

At study intake, EAs (n = 10) reported greater past-year intravenous drug use and greater employment, legal, and psychiatric severity (p's < .05) compared to OAs (n = 25). Despite these initial differences, there were no significant differences in the percentages of urine specimens testing negative for illicit opioids between EA and OA participants at Study Week 4 (90 % vs. 88 %, p = .99), Week 8 (80 % vs. 76 %, p = .99) or Week 12 (60 % vs. 68 %, p = .71). Relative to their older peers, EAs also demonstrated significantly greater improvements on the BAI, BDI-II, and ASI Employment and Legal subscales (p's < .05).

Conclusions

Despite presenting with greater past-year intravenous drug use and psychosocial severity relative to OAs, EAs responded favorably to the IBT intervention.

SUBMITTER: Peck KR

PROVIDER: S-EPMC7108757 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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Publications

Effects of Interim Buprenorphine Treatment for opioid use disorder among emerging adults.

Peck Kelly R KR Ochalek Taylor A TA Badger Gary J GJ Sigmon Stacey C SC

Drug and alcohol dependence 20200122

<h4>Objective</h4>Although opioid maintenance is a first-line approach for treating opioid use disorder (OUD), suboptimal treatment outcomes have been reported among emerging adults (EAs; 18-25 years of age). In this secondary analysis, we compared treatment outcomes between EAs and older adults (OAs; ≥ 26 years of age) receiving low-barrier, technology-assisted Interim Buprenorphine Treatment (IBT) during waitlist delays to comprehensive opioid maintenance treatment.<h4>Method</h4>Participants ...[more]

PMID: 31991327

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Dataset Information

Effects of Interim Buprenorphine Treatment for opioid use disorder among emerging adults.

Objective

Method

Results

Conclusions

Publications

Effects of Interim Buprenorphine Treatment for opioid use disorder among emerging adults.

Similar Datasets

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