Unknown

Dataset Information

0

Impact of community piped water coverage on re-infection with urogenital schistosomiasis in rural South Africa.


ABSTRACT: Previously, we demonstrated that coverage of piped water in the seven years preceding a parasitological survey was strongly predictive of Schistosomiasis haematobium infection in a nested cohort of 1976 primary school children (Tanser, 2018). Here, we report on the prospective follow up of infected members of this nested cohort (N = 333) for two successive rounds following treatment. Using a negative binomial regression fitted to egg count data, we found that every percentage point increase in piped water coverage was associated with 4.4% decline in intensity of re-infection (incidence rate ratio = 0.96, 95% CI: 0.93-0.98, p=0.004) among the treated children. We therefore provide further compelling evidence in support of the scaleup of piped water as an effective control strategy against Schistosoma haematobium transmission.

SUBMITTER: Mogeni P 

PROVIDER: S-EPMC7108860 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

altmetric image

Publications

Impact of community piped water coverage on re-infection with urogenital schistosomiasis in rural South Africa.

Mogeni Polycarp P   Vandormael Alain A   Cuadros Diego D   Appleton Christopher C   Tanser Frank F  

eLife 20200317


Previously, we demonstrated that coverage of piped water in the seven years preceding a parasitological survey was strongly predictive of <i>Schistosomiasis haematobium</i> infection in a nested cohort of 1976 primary school children (Tanser, 2018). Here, we report on the prospective follow up of infected members of this nested cohort (N = 333) for two successive rounds following treatment. Using a negative binomial regression fitted to egg count data, we found that every percentage point increa  ...[more]

Similar Datasets

| S-EPMC5819946 | biostudies-literature
| S-EPMC8669071 | biostudies-literature
| S-EPMC9801593 | biostudies-literature
| S-EPMC5815575 | biostudies-other
| S-EPMC8345861 | biostudies-literature
| S-EPMC8786241 | biostudies-literature
| S-EPMC3710142 | biostudies-literature
| S-EPMC5676974 | biostudies-literature
| S-EPMC6531856 | biostudies-literature
| S-EPMC4255272 | biostudies-literature