Unknown

Dataset Information

0

Engineered cartilage utilizing fetal cartilage-derived progenitor cells for cartilage repair.


ABSTRACT: The aim of this study was to develop a fetal cartilage-derived progenitor cell (FCPC) based cartilage gel through self-assembly for cartilage repair surgery, with clinically useful properties including adhesiveness, plasticity, and continued chondrogenic remodeling after transplantation. Characterization of the gels according to in vitro self-assembly period resulted in increased chondrogenic features over time. Adhesion strength of the cartilage gels were significantly higher compared to alginate gel, with the 2-wk group showing a near 20-fold higher strength (1.8?±?0.15 kPa vs. 0.09?±?0.01 kPa, p?

SUBMITTER: Park DY 

PROVIDER: S-EPMC7109068 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

altmetric image

Publications

Engineered cartilage utilizing fetal cartilage-derived progenitor cells for cartilage repair.

Park Do Young DY   Min Byoung-Hyun BH   Park So Ra SR   Oh Hyun Ju HJ   Truong Minh-Dung MD   Kim Mijin M   Choi Ja-Young JY   Park In-Su IS   Choi Byung Hyune BH  

Scientific reports 20200331 1


The aim of this study was to develop a fetal cartilage-derived progenitor cell (FCPC) based cartilage gel through self-assembly for cartilage repair surgery, with clinically useful properties including adhesiveness, plasticity, and continued chondrogenic remodeling after transplantation. Characterization of the gels according to in vitro self-assembly period resulted in increased chondrogenic features over time. Adhesion strength of the cartilage gels were significantly higher compared to algina  ...[more]

Similar Datasets

| S-EPMC4878331 | biostudies-literature
| S-EPMC6719489 | biostudies-literature
| S-EPMC7862470 | biostudies-literature
| S-EPMC6805685 | biostudies-literature
| S-EPMC3461098 | biostudies-literature
| S-EPMC7116023 | biostudies-literature
| S-EPMC6171703 | biostudies-literature
| S-EPMC5809641 | biostudies-literature
| S-EPMC8633594 | biostudies-literature
| S-EPMC6441183 | biostudies-literature