Ontology highlight
ABSTRACT:
SUBMITTER: Azeredo LA
PROVIDER: S-EPMC7111449 | biostudies-literature | 2017 Apr-Jun
REPOSITORIES: biostudies-literature
Azeredo Lucas A de LA De Nardi Tatiana T Levandowski Mateus L ML Tractenberg Saulo G SG Kommers-Molina Julia J Wieck Andrea A Irigaray Tatiana Q TQ Silva Irênio G da IGD Grassi-Oliveira Rodrigo R
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20170112 2
<h4>Objective:</h4>Memory impairment is an important contributor to the reduction in quality of life experienced by older adults, and genetic risk factors seem to contribute to variance in age-related cognitive decline. Brain-derived neurotrophic factor (BDNF) is an important nerve growth factor linked with development and neural plasticity. The Val66Met polymorphism in the BDNF gene has been associated with impaired episodic memory in adults, but whether this functional variant plays a role in ...[more]