Ontology highlight
ABSTRACT:
SUBMITTER: Zhao S
PROVIDER: S-EPMC7111762 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Zhao Shanshan S Gao Qi Q Lin Jian J Yan Mengfei M Yu Qinghua Q Yang Qian Q
Research in veterinary science 20140919 3
Exposure of piglets less than 2 weeks of age to virulent transmissible gastroenteritis virus (TGEV) gives rise to mortality as high as 100%, and adult pigs recovering from its infection often become TGEV carriers. These facts suggest an evasion of the immune system by virulent TGEV. In this study, we showed that a virulent TGEV SHXB strain could infect porcine immature monocyte-derived dendritic cells (Mo-DCs), and down-regulate cell surface markers (SLA-II-DR, CD1a and CD80/86). Moreover, SHXB- ...[more]