Ontology highlight
ABSTRACT:
SUBMITTER: Vijgen L
PROVIDER: S-EPMC7111800 | biostudies-literature | 2005 Jun
REPOSITORIES: biostudies-literature
Vijgen Leen L Keyaerts Els E Lemey Philippe P Moës Elien E Li Sandra S Vandamme Anne-Mieke AM Van Ranst Marc M
Virology 20050601 1
In this study, we report the complete genome sequence of two contemporary human coronavirus OC43 (HCoV-OC43) strains detected in 2003 and 2004, respectively. Comparative genetic analyses of the circulating strains and the prototype HCoV-OC43 strain (ATCC VR759) were performed. Remarkably, a lower than expected similarity is found between the complete genomes and more in particular between the spike genes of the BE03 and BE04 strains. This finding suggests the existence of two genetically distinc ...[more]