Ontology highlight
ABSTRACT:
SUBMITTER: Hayashi T
PROVIDER: S-EPMC7111900 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Hayashi Tsuyoshi T Chaichoune Kridsada K Patchimasiri Tuangthong T Hiromoto Yasuaki Y Kawasaki Yuri Y Wiriyarat Witthawat W Chakritbudsabong Warunya W Prayoonwong Natanan N Chaisilp Natnapat N Parchariyanon Sujira S Ratanakorn Parntep P Uchida Yuko Y Tsuda Tomoyuki T Saito Takehiko T
Virology 20110119 1
In Thailand, highly pathogenic avian influenza (HPAI) viruses of subtype H5N1 had been isolated from various wild birds during the HPAI outbreak in poultries. In this study, we examined the pathogenicity of two wild bird isolates (A/Pigeon/Thailand/VSMU-7-NPT/2004; Pigeon04 and A/Tree sparrow/Ratchaburi/VSMU-16-RBR/2005; T.sparrow05) in mice. They showed similar replication in several organs and lethal outcome. However, on day 3 post-infection, Pigeon04 induced mRNA expression of proinflammatory ...[more]