Ontology highlight
ABSTRACT:
SUBMITTER: Cruz DJ
PROVIDER: S-EPMC7111992 | biostudies-literature | 2006 Oct
REPOSITORIES: biostudies-literature
Cruz Deu John M DJ Kim Chul-Joong CJ Shin Hyun-Jin HJ
Virology 20060901 1
Seven-mer phage random peptide libraries were panned against 2C10, a monoclonal antibody that showed neutralizing activities against PEDV. Recombinant M13 phages displaying the peptides SHRLP(Y/Q)(P/V) or GPRPVTH on the g3p minor coat protein showed strong binding affinity with 2C10 (70% and 30% of recovered phages, respectively) after multiple panning. Sequence analysis suggested that these peptides are similar with (1368)GPRLQPY(1374) found at the carboxy-terminal of the S protein. In neutrali ...[more]