Ontology highlight
ABSTRACT:
SUBMITTER: Hao Z
PROVIDER: S-EPMC7112615 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Hao Zhichao Z Fu Fang F Cao Liyan L Guo Longjun L Liu Jianbo J Xue Mei M Feng Li L
Molecular immunology 20190218
p53 is a tumor suppressor gene that can be activated in many contexts, such as DNA damage or stressful conditions. p53 has also been shown to be important for responses to certain viral infections. Porcine epidemic diarrhea virus (PEDV) is a major enteric pathogen of the coronavirus family that causes extensive mortality among piglets. The involvement of p53 during PEDV infection has not previously been investigated. In this study, we detected p53 upregulation in response to PEDV infection. Trea ...[more]