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Systemic Hyperalgesia in Females with Gulf War Illness, Chronic Fatigue Syndrome and Fibromyalgia.


ABSTRACT: Pain is a diagnostic criterion for Gulf War Illness (GWI), Chronic Fatigue Syndrome (CFS), and fibromyalgia (FM). The physical sign of systemic hyperalgesia (tenderness) was assessed in 920 women who were stratified by 2000 Kansas GWI, 1994 CFS, and 1990 FM criteria. Pressure was applied by dolorimetry at 18 traditional tender points and the average pressure causing pain determined. GWI women were the most tender (2.9?±?1.6?kg, mean ± SD, n?=?70), followed by CFS/FM (3.1?±?1.4?kg, n?=?196), FM (3.9?±?1.4?kg, n?=?56), and CFS (5.8?±?2.1?kg, n?=?170) compared to controls (7.2?±?2.4?kg, significantly highest by Mann-Whitney tests p?

SUBMITTER: Surian AA 

PROVIDER: S-EPMC7113257 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Systemic Hyperalgesia in Females with Gulf War Illness, Chronic Fatigue Syndrome and Fibromyalgia.

Surian Amber A AA   Baraniuk James N JN  

Scientific reports 20200401 1


Pain is a diagnostic criterion for Gulf War Illness (GWI), Chronic Fatigue Syndrome (CFS), and fibromyalgia (FM). The physical sign of systemic hyperalgesia (tenderness) was assessed in 920 women who were stratified by 2000 Kansas GWI, 1994 CFS, and 1990 FM criteria. Pressure was applied by dolorimetry at 18 traditional tender points and the average pressure causing pain determined. GWI women were the most tender (2.9 ± 1.6 kg, mean ± SD, n = 70), followed by CFS/FM (3.1 ± 1.4 kg, n = 196), FM (  ...[more]

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