Ontology highlight
ABSTRACT:
SUBMITTER: Wohrle J
PROVIDER: S-EPMC7113318 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Wöhrle Johannes J Krämer Stefan D SD Meyer Philipp A PA Rath Christin C Hügle Matthias M Urban Gerald A GA Roth Günter G
Scientific reports 20200401 1
In this work we show how DNA microarrays can be produced batch wise on standard microscope slides in a fast, easy, reliable and cost-efficient way. Contrary to classical microarray generation, the microarrays are generated via digital solid phase PCR. We have developed a cavity-chip system made of a PDMS/aluminum composite which allows such a solid phase PCR in a scalable and easy to handle manner. For the proof of concept, a DNA pool composed of two different DNA species was used to show that d ...[more]