Ontology highlight
ABSTRACT:
SUBMITTER: Saha A
PROVIDER: S-EPMC7113671 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Saha Amrita A Bhagyawant Sameer S SS Parida Manmohan M Dash Paban Kumar PK
Antiviral research 20160823
Chikungunya virus (CHIKV) has emerged as one of the most significant arboviral threats in many parts of the world. In spite of large scale morbidity, and long lasting polyarthralgia, no licensed vaccine or antivirals are available for the clinical management of CHIKV infection. In this study, a novel RNA interference based strategy has been adopted for effective inhibition of CHIKV. Four artificial microRNAs (amiRNAs) were designed to target different regions of CHIKV genome. These amiRNAs signi ...[more]