Ontology highlight
ABSTRACT:
SUBMITTER: Martin B
PROVIDER: S-EPMC7113884 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Martin Baptiste B Hoenen Thomas T Canard Bruno B Decroly Etienne E
Antiviral research 20160914
This review focuses on the recent progress in our understanding of filovirus protein structure/function and its impact on antiviral research. Here we focus on the surface glycoprotein GP<sub>1,2</sub> and its different roles in filovirus entry. We first describe the latest advances on the characterization of GP gene-overlapping proteins sGP, ssGP and Δ-peptide. Then, we compare filovirus surface GP<sub>1,2</sub> proteins in terms of structure, synthesis and function. As they bear potential in dr ...[more]