Ontology highlight
ABSTRACT:
SUBMITTER: Liu RY
PROVIDER: S-EPMC7114075 | biostudies-literature | 2005 Sep
REPOSITORIES: biostudies-literature
Liu Ran-Yi RY Wu Li-Zhi LZ Huang Bi-Jun BJ Huang Jia-Ling JL Zhang Yan-Ling YL Ke Miao-La ML Wang Jun-Mei JM Tan Wei-Ping WP Zhang Ru-Hua RH Chen Han-Kui HK Zeng Yi-Xin YX Huang Wenlin W
Virus research 20050901 1-2
The causative agent of severe acute respiratory syndrome (SARS) has been identified as SARS-associated coronavirus (SARS-CoV), but the prophylactic treatment of SARS-CoV is still under investigation. We constructed a recombinant adenovirus containing a truncated N-terminal fragment of the SARS-CoV Spike (S) gene (from--45 to 1469, designated Ad-S(N)), which encoded a truncated S protein (490 amino-acid residues, a part of 672 amino-acid S1 subunit), and investigated whether this construct could ...[more]