Ontology highlight
ABSTRACT:
SUBMITTER: Wen JS
PROVIDER: S-EPMC7114202 | biostudies-literature | 2008 Mar
REPOSITORIES: biostudies-literature
Virus research 20071203 1-2
In this study, we tried to identify dengue virus-specific CD4(+) T-cell epitopes, which can induce PBMC (peripheral blood mononuclear cells) isolated from DF convalescent patients (dengue virus type 1 infection) to secrete IFN-gamma. PBMC of DF convalescent patients were stimulated in vitro with dengue virus-derived peptides, which were prepared based on the prediction of dengue virus-specific CD4(+) T-cell epitopes by using RANKpep online software. Subsequently, the frequency of IFN-gamma produ ...[more]