Serum zinc levels and multiple health outcomes: Implications for zinc-based biomaterials.

ABSTRACT:

Background

Zinc-based biomaterials, including biodegradable metal, nanoparticles, and coatings used in medical implants release zinc ions that may increase the whole-body and serum zinc concentrations. The impact of serum zinc concentrations on major health outcomes can provide insights for device design and clinical transformation of zinc-based biomaterials.

Methods

This nationally representative cross-sectional study enrolled participants from the National Health and Nutrition Examination Survey (NHANES, 2011-2014) including 3607 participants. Using unadjusted and multivariate-adjusted logistic regression analyses, two-piecewise linear regression model with a smoothing function and threshold level analysis, we evaluated the associations between elevated serum zinc levels a

SUBMITTER: Qu X 

PROVIDER: S-EPMC7114479 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature