Ontology highlight
ABSTRACT:
SUBMITTER: Abid Q
PROVIDER: S-EPMC7115721 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
American journal of kidney diseases : the official journal of the National Kidney Foundation 20191007 2
Apolipoprotein L1 (APOL1) risk variants G1 and G2 are known to result in risk for kidney disease in patients of African ancestry. APOL1-associated nephropathy typically occurs in association with certain environmental factors or systemic diseases. As such, there has been increasing evidence of the role of interferon (IFN) pathways in the pathogenesis of APOL1-associated collapsing glomerulopathy in patients with human immunodeficiency virus (HIV) infection and systemic lupus erythematosus, 2 con ...[more]