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Origins and genetic legacy of prehistoric dogs.


ABSTRACT: Dogs were the first domestic animal, but little is known about their population history and to what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that all dogs share a common ancestry distinct from present-day wolves, with limited gene flow from wolves since domestication but substantial dog-to-wolf gene flow. By 11,000 years ago, at least five major ancestry lineages had diversified, demonstrating a deep genetic history of dogs during the Paleolithic. Coanalysis with human genomes reveals aspects of dog population history that mirror humans, including Levant-related ancestry in Africa and early agricultural Europe. Other aspects differ, including the impacts of steppe pastoralist expansions in West and East Eurasia and a near-complete turnover of Neolithic European dog ancestry.

SUBMITTER: Bergstrom A 

PROVIDER: S-EPMC7116352 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Origins and genetic legacy of prehistoric dogs.

Bergström Anders A   Frantz Laurent L   Schmidt Ryan R   Ersmark Erik E   Lebrasseur Ophelie O   Girdland-Flink Linus L   Lin Audrey T AT   Storå Jan J   Sjögren Karl-Göran KG   Anthony David D   Antipina Ekaterina E   Amiri Sarieh S   Bar-Oz Guy G   Bazaliiskii Vladimir I VI   Bulatović Jelena J   Brown Dorcas D   Carmagnini Alberto A   Davy Tom T   Fedorov Sergey S   Fiore Ivana I   Fulton Deirdre D   Germonpré Mietje M   Haile James J   Irving-Pease Evan K EK   Jamieson Alexandra A   Janssens Luc L   Kirillova Irina I   Horwitz Liora Kolska LK   Kuzmanovic-Cvetković Julka J   Kuzmin Yaroslav Y   Losey Robert J RJ   Dizdar Daria Ložnjak DL   Mashkour Marjan M   Novak Mario M   Onar Vedat V   Orton David D   Pasarić Maja M   Radivojević Miljana M   Rajković Dragana D   Roberts Benjamin B   Ryan Hannah H   Sablin Mikhail M   Shidlovskiy Fedor F   Stojanović Ivana I   Tagliacozzo Antonio A   Trantalidou Katerina K   Ullén Inga I   Villaluenga Aritza A   Wapnish Paula P   Dobney Keith K   Götherström Anders A   Linderholm Anna A   Dalén Love L   Pinhasi Ron R   Larson Greger G   Skoglund Pontus P  

Science (New York, N.Y.) 20201029 6516


Dogs were the first domestic animal, but little is known about their population history and to what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that all dogs share a common ancestry distinct from present-day wolves, with limited gene flow from wolves since domestication but substantial dog-to-wolf gene flow. By 11,000 years ago, at least five major ancestry lineages had diversified, demonstrating a deep genetic history of dogs during the Paleolithic. Coanalysis  ...[more]

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