Gut microbiota and their metabolites in the progression of non-alcoholic fatty liver disease.
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ABSTRACT:
SUBMITTER: Zhou J
PROVIDER: S-EPMC7116620 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Publications
Gut microbiota and their metabolites in the progression of non-alcoholic fatty liver disease.
Zhou Jin J Tripathi Madhulika M Sinha Rohit A RA Singh Brijesh Kumar BK Yen Paul M PM
Hepatoma research 20210113
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disorder worldwide. It comprises a spectrum of conditions that range from steatosis to non-alcoholic steatohepatitis, with progression to cirrhosis and hepatocellular carcinoma. Currently, there is no FDA-approved pharmacological treatment for NAFLD. The pathogenesis of NAFLD involves genetic and environmental/host factors, including those that cause changes in intestinal microbiota and their metabolites. In this review, we di ...[more]
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