Ontology highlight
ABSTRACT:
SUBMITTER: Borg M
PROVIDER: S-EPMC7116658 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Nature cell biology 20200511 6
Epigenetic marks are reprogrammed in the gametes to reset genomic potential in the next generation. In mammals, paternal chromatin is extensively reprogrammed through the global erasure of DNA methylation and the exchange of histones with protamines<sup>1,2</sup>. Precisely how the paternal epigenome is reprogrammed in flowering plants has remained unclear since DNA is not demethylated and histones are retained in sperm<sup>3,4</sup>. Here, we describe a multi-layered mechanism by which H3K27me3 ...[more]