Ontology highlight
ABSTRACT:
SUBMITTER: Tian L
PROVIDER: S-EPMC7117539 | biostudies-literature | 2008 Dec
REPOSITORIES: biostudies-literature
Tian Lang L Wang Hong-ning HN Lu Dan D Zhang Yun-fei YF Wang Ting T Kang Run-ming RM
Biochemical and biophysical research communications 20081007 1
Epitope-based vaccines designed to induce cellular immune response and antibody responses specific for infectious bronchitis virus (IBV) are being developed as a means for increasing vaccine potency. In this study, we selected seven epitopes from the spike (S1), spike (S2), and nucleocapsid (N) protein and constructed a multi-epitope DNA vaccine. The 7-day-old chickens were immunized intramuscularly with multi-epitope DNA vaccine encapsulated by liposome and boosted two weeks later, and were cha ...[more]