Ontology highlight
ABSTRACT:
SUBMITTER: Yu S
PROVIDER: S-EPMC7117689 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
PloS one 20200402 4
Systematic interrogation of tumor-infiltrating immune cells (TIICs) is key to the prediction of clinical outcome and development of immunotherapies. However, little is known about the TIICs of hepatocellular carcinoma (HCC) and its impact on the prognosis of patients and potential for immunotherapy. We applied CIBERSORT of 1090 tumors to infer the infiltration of 22 subsets of TIICs using gene expression data. Unsupervised clustering analysis by 22 TIICs revealed 4 clusters of tumors, mainly def ...[more]