Skin sympathetic nerve activity and ventricular rate control during atrial fibrillation.

ABSTRACT:

Background

The relationship between the ventricular rate (VR) during atrial fibrillation (AF) and skin sympathetic nerve activity (SKNA) remains unclear.

Objective

The purpose of this study was to test the hypothesis that SKNA bursts accelerate VR during AF.

Methods

We simultaneously recorded electrocardiogram and SKNA in 8 patients (median age 66.0 years [interquartile range {IQR} 59.0-77.0 years]; 4 men [50%]) with 30 paroxysmal AF episodes (all >10-minute long) and 12 patients (73.0 years [IQR 60.5-80.0 years]; 6 men [50%]) with persistent AF. The average amplitude of SKNA (aSKNA [μV]) during AF was analyzed in 1-minute windows and binned, showing 2 Gaussian distributions. We used the mean + 3SD of the first Gaussian distribution as the threshold that separates bur

SUBMITTER: Kusayama T 

PROVIDER: S-EPMC7117970 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature