Antibacterial effects of nanopillar surfaces are mediated by cell impedance, penetration and induction of oxidative stress.
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ABSTRACT:
SUBMITTER: Jenkins J
PROVIDER: S-EPMC7118135 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
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Antibacterial effects of nanopillar surfaces are mediated by cell impedance, penetration and induction of oxidative stress.
Jenkins J J Mantell J J Neal C C Gholinia A A Verkade P P Nobbs A H AH Su B B
Nature communications 20200402 1
Some insects, such as dragonflies, have evolved nanoprotrusions on their wings that rupture bacteria on contact. This has inspired the design of antibacterial implant surfaces with insect-wing mimetic nanopillars made of synthetic materials. Here, we characterise the physiological and morphological effects of mimetic titanium nanopillars on bacteria. The nanopillars induce deformation and penetration of the Gram-positive and Gram-negative bacterial cell envelope, but do not rupture or lyse bacte ...[more]
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