Unknown

Dataset Information

0

Hepatitis E virus seroprevalence in pets in the Netherlands and the permissiveness of canine liver cells to the infection.


ABSTRACT: Hepatitis E virus (HEV) as an emerging zoonotic pathogen causes a major public health issue. Transmission from domestic, wildlife and zoo animals to human has been widely reported. Whether pets also serve as reservoirs remains an intriguing question. In this study, we found the sero-positive rates of HEV-specific antibodies in pet dogs, cats and horses of 18.52% (30/162), 14.89% (7/47) and 18.18% (4/22) in the Netherlands. Although HEV viral RNA was not detected in these animals, we have demonstrated that dog liver cells are susceptible to HEV infection in vitro. These results call more attention to address the potential role of pets in the zoonotic transmission of HEV.

SUBMITTER: Li Y 

PROVIDER: S-EPMC7119158 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

altmetric image

Publications

Hepatitis E virus seroprevalence in pets in the Netherlands and the permissiveness of canine liver cells to the infection.

Li Yunlong Y   Qu Changbo C   Spee Bart B   Zhang Ruyi R   Penning Louis C LC   de Man Robert A RA   Peppelenbosch Maikel P MP   Fieten Hille H   Pan Qiuwei Q  

Irish veterinary journal 20200402


Hepatitis E virus (HEV) as an emerging zoonotic pathogen causes a major public health issue. Transmission from domestic, wildlife and zoo animals to human has been widely reported. Whether pets also serve as reservoirs remains an intriguing question. In this study, we found the sero-positive rates of HEV-specific antibodies in pet dogs, cats and horses of 18.52% (30/162), 14.89% (7/47) and 18.18% (4/22) in the Netherlands. Although HEV viral RNA was not detected in these animals, we have demonst  ...[more]

Similar Datasets

| S-EPMC6296558 | biostudies-literature
| S-EPMC7713078 | biostudies-literature
| S-EPMC3358074 | biostudies-literature
| S-EPMC8604763 | biostudies-literature
| S-EPMC3372335 | biostudies-literature
| S-EPMC112089 | biostudies-literature
| S-EPMC5856341 | biostudies-literature
| S-EPMC4581219 | biostudies-literature
| S-EPMC6518518 | biostudies-literature
| S-EPMC5724202 | biostudies-literature