Dataset Information
Palladium-catalyzed ?,?-dehydrogenation of acyclic ester equivalents promoted by a novel electron deficient phosphinooxazoline ligand.
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ABSTRACT:
SUBMITTER: Fulton TJ
PROVIDER: S-EPMC7119178 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Publications
Palladium-catalyzed α,β-dehydrogenation of acyclic ester equivalents promoted by a novel electron deficient phosphinooxazoline ligand.
Tetrahedron 20190601 31
A unique example of Pd-catalyzed decarboxylative dehydrogenation of fully substituted <i>N</i>-acyl allyl enol carbonates is enabled by a new electron deficient phosphinooxazoline (PHOX) ligand. The reaction proceeds from the <i>Z</i>-enol carbonate to provide dehydrogenation products exclusively in high <i>E/Z</i> selectivity, while the <i>E</i>-enol carbonate provides the α-allylation product with only minor dehydrogenation. The reaction proceeds with a broad scope of (<i>Z</i>)-enol carbonate ...[more]