Ontology highlight
ABSTRACT:
SUBMITTER: Barwe SP
PROVIDER: S-EPMC7120351 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Barwe Sonali P SP Gopalakrisnapillai Anilkumar A Mahajan Nitin N Druley Todd E TE Kolb E Anders EA Crowgey Erin L EL
Genomics & informatics 20200331 1
Acute leukemia represents the most common pediatric malignancy comprising diverse subtypes with varying prognosis and treatment outcomes. New and targeted treatment options are warranted for this disease. Patient-derived xenograft (PDX) models are increasingly being used for preclinical testing of novel treatment modalities. A novel approach involving targeted error-corrected RNA sequencing using ArcherDX HemeV2 kit was employed to compare 25 primary pediatric acute leukemia samples and their co ...[more]