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Beyond Mfold: recent advances in RNA bioinformatics.


ABSTRACT: Computational analysis of RNA secondary structure is a classical field of biosequence analysis, which has recently gained momentum due to the manyfold regulatory functions of RNA that have become apparent. We present five recent computational approaches that address the problems of synoptic folding space analysis, pseudoknot prediction, structure alignment, comparative structure prediction, and miRNA target prediction. All these programs are in current use and are available via the Bielefeld Bioinformatics Server at .

SUBMITTER: Reeder J 

PROVIDER: S-EPMC7125698 | biostudies-literature | 2006 Jun

REPOSITORIES: biostudies-literature

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Beyond Mfold: recent advances in RNA bioinformatics.

Reeder Jens J   Höchsmann Matthias M   Rehmsmeier Marc M   Voss Björn B   Giegerich Robert R  

Journal of biotechnology 20060310 1


Computational analysis of RNA secondary structure is a classical field of biosequence analysis, which has recently gained momentum due to the manyfold regulatory functions of RNA that have become apparent. We present five recent computational approaches that address the problems of synoptic folding space analysis, pseudoknot prediction, structure alignment, comparative structure prediction, and miRNA target prediction. All these programs are in current use and are available via the Bielefeld Bio  ...[more]

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