Ontology highlight
ABSTRACT:
SUBMITTER: Rizzelli F
PROVIDER: S-EPMC7125961 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Open biology 20200318 3
Mitotic progression is orchestrated by morphological and mechanical changes promoted by the coordinated activities of the microtubule (MT) cytoskeleton, the actin cytoskeleton and the plasma membrane (PM). MTs assemble the mitotic spindle, which assists sister chromatid separation, and contact the rigid and tensile actomyosin cortex rounded-up underneath the PM. Here, we highlight the dynamic crosstalk between MTs, actin and cell membranes during mitosis, and discuss the molecular connections be ...[more]